Region Hovedstaden

Region Hovedstaden

Blegdamsvej 9, 2100 København Ø

PhD, CHIP - Centre of Excellence for Health, Immunity and Infections, Dept. of Infectious Diseases, Rigshospitalet

We are looking for a full-time PhD student for a project at CHIP - an academic research Centre of Excellence with offices at the Department of Infectious Diseases at Rigshospitalet.  
 
Human immunodeficiency virus (HIV) infection results in more than a million deaths per year. The infection can be controlled with antiretroviral therapy that suppresses viral replication. Nonetheless, replication still occurs and genetic diversity is generated in the viral population. This results in the selection of drug resistance mutations (DRMs) that make the virus more resistant to treatment. The aim of the current project is to characterize inter- and intra-patient viral population diversity, including identification of DRMs, to increase our understanding of the genetic determinants of HIV infection and guide the design of treatment strategies.
 
As coordinating center for international trials, CHIP is a leader in the field of conducting international clinical and observational research involving patients with HIV or other infectious diseases. CHIP is a dynamic group with 45 full-time employees and satellite offices in Germany, Spain and United Kingdom.  
 
For further information, please visit our websites: www.chip.dk and www.persimune.org  
 
The position is initially for a one year period where you and key PM researchers will prepare a research protocol forming the basis for the submission of a PhD application to the University of Copenhagen. The application should be submitted within 6 months of the hiring date. Depending on the outcome, the position will be extended for the duration of the PhD study.  
 
The advisors for this PhD position will be medical doctors, biostatisticians and computational biologists with experience in the scientific area – affiliated with CHIP, University College London, London, UK and Institute Pasteur, Paris, France. The supervisors will oversee the development of the PhD application and act as advisors during the course of the PhD study.  
 
Qualifications  
You may be a trained physician or hold a relevant masters degree and have documented research experience. You have excellent IT and communication skills and are able to use English as working language.  
We are looking for a candidate with hands-on experience with viral nucleic acid extraction, reverse transcription and amplification of virus genomes, and next generation sequencing (NGS). The candidate must also possess skills within bioinformatics, especially high-throughput sequence analysis and phylogenetics. As such, the candidate need skills to establish a state-of-the-art NGS platform for the end-to-end genetic analyses of viral populations, including HIV, but also applicable to other virus relevant the hospital. The candidate is expected to develop a number of scientific manuscripts in collaboration with domestic and foreign experts within genetics and virology.  
 
Conditions  
Salary and employment conditions are in accordance with current public agreements between the Capital Region of Copenhagen and AC. Your work place will be CHIP offices at the Rigshospitalet. The position is funded by research grants. We want to reflect the surrounding society and encourage everyone regardless of personal background to apply.  
 
For further information, please contact Professor Jens Lundgren, director of CHIP, phone: 35 45 57 51 or mail: jens.lundgren@regionh.dk. Interested applicants should apply before January 22, 2017. Application should include a CV, a cover letter expressing your interest and motivation, and any relevant publications.  
 

  • Fakta

  • Arbejdssted
    Rigshospitalet, Blegdamsvej
  • Kontaktperson
    Jens Lundgren
  • Adresse
    Blegdamsvej 9, 2100 København Ø
  • Stillingstype
    Forsker
  • Speciale
    Intern medicin: Infektionsmedicin
  • Ansættelsesform
    Tidsbegrænset periode
  • Ugentlig arbejdstid
    Fuld tid
  • Ansættelsens start
    Snarest muligt
  • Regionens jobnr.
    203668
  • Quick-nr.
    313746
  • Indrykningsdato
    09-01-2017
  • Ansøgningsfrist
    22-01-2017 (udløbet)


  • Fakta

  • Arbejdssted
    Rigshospitalet, Blegdamsvej
  • Adresse
    Blegdamsvej 9, 2100 København Ø
  • Kontaktperson
    Jens Lundgren
  • Stillingstype
    Forsker
  • Speciale
    Intern medicin: Infektionsmedicin
  • Ansættelsesform
    Tidsbegrænset periode
  • Ugentlig arbejdstid
    Fuld tid
  • Ansættelsens start
    Snarest muligt
  • Regionens jobnr.
    203668
  • Quick-nr.
    313746
  • Indrykningsdato
    09-01-2017
  • Ansøgningsfrist
    22-01-2017 (udløbet)
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