2 Post Doc positions in molecular cancer research at University of Copenhagen and Rigshospitalet The Capital Region of Denmark
2 Post Doc positions are open as part of a newly established international
programme on novel familial breast cancer factors. The positions are for highly motivated researchers
with a desire to unravel new genetic risk
factors and pathways in breast cancer as well as possible therapeutic
interventions.
Our research
The goals of the current projects are to
understand familial breast cancer by identifying genetic risk factors that can be
exploited in the current management of breast cancer patients (see the
following recent publications, pubmed IDs: 27515922; 27323328; 27113759; 26805514;
25953507, 27734835).
Projects and work places
Project 1, RH
Cilius Nielsen
The project aims to identify novel breast cancer
predisposing genes by means of WES and WGS and characterize tumors and the
clinical features of affected patients. The Post Doc will be located at Rigshospitalets
Center for Genomic Medicine where we perform NGS and array based breast cancer
analysis for the Capital Region of Denmark. The Post Doc will be involved in
NGS based mapping of novel genetic variants in HBOC and classification, LOH
etc. and analysis of mutations in breast tumors. More information on the Centre for Genomic Medicine on https://www.rigshospitalet.dk/afdelinger-og-klinikker/diagnostisk/genomisk-medicin. For further information regarding the position,
please contact Professor Finn Cilius Nielsen on e-mail fcn@rh.dk
Project 2,
UCPH Sørensen
Our breast
cancer consortium has applied exome sequencing to identify new factors that
guard against breast cancer. The post doc will run medium-scale siRNA screens
and validate high scoring factors with CRISPR-Cas9 modified cell models. The
post doc will then unravel high scoring factors functional and mechanistic
roles with focus on biochemical and cell biological approaches.
Our group
consists of 10 dedicated researchers, and we have excellent research facilities in modern
laboratories. More
information on the Sørensen group on http://www.bric.ku.dk/research/Sorensen_Group/ For further
information regarding the position, please contact Associate Professor Claus
Storgaard Sørensen on e-mail
claus.storgaard@bric.ku.dk.
Start: Preferably October 1st 2017 or after agreement
Duration: Both project are for 2 years. Up to 3 years additional employment
is possible, so the total duration can be up to 5 years.
Qualifications
We expect you to be a
highly motivated and highly ambitious scientist with the following
qualifications:
- A PhD in Medicine or Life Sciences with focus on cancer biology, cancer genetics, biochemistry or similar
- A desire to make a difference through highly dedicated research
- Experimental expertise in genome maintenance pathways or cancer genetics
- Excellent English skills written and spoken
- For project 1: The successful applicant has experience in clinical and/or molecular genetics and high throughput NGS and array based analysis of cancers and in particular mutation mapping and characterization.
- For project 2: The preferred candidates have experience in generating CRISPR-Cas9 cell lines as well as documented experience in cell biology, molecular biology, and biochemistry
Places of employment
Project 1
The Centre for Genomic Medicine was established in
2010 as a strategic initiative to bring genome wide technologies to patient
care. The laboratory is located in Rigshospitalet and is currently one of
Denmark largest providers of molecular analysis. In connection to this project,
we have established comprehensive analytic pipeline for solid cancers composed
of tumor mutations, CNVs and expression profiles of the tumors and germline,
that is comparable to any standard at a global level. The laboratory currently
comprises about 40 technicians and academic personnel. and we aim at expanding
with a newly established bioinformatics section.
Project 2
The employment
is at BRIC, University of Copenhagen. BRIC is located in the Biocenter, close
to the centre of Copenhagen. We offer creative and stimulating working conditions in a dynamic and
international research environment. Our research facilities include modern
laboratories and a number of
core facilities shared between the 23 research groups at BRIC and the
neighboring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers
and a young researchers club ASAP and our own PhD programme, MoMeD and our own Postdoc Career Programme. BRIC actively participates
in the European alliance, EU-life consisting of 13 excellent life science
research institutions http://eu-life.eu/
Please read more about the Sørensen
research group and BRIC on http://www.bric.ku.dk/
Terms of salary and employment, and the further process
Salary, pension and terms
of employment will be in accordance with the agreement between the Ministry of
Finance and The Academics Central organization. Currently, the monthly salary
starts at 32,745 DKK/ca. 4,366 Euro plus pension. Depending on qualifications,
a higher salary may be negotiated.
Non-Danish and Danish
applicants may be eligible for tax reductions, if they hold a PhD degree and
have not lived in Denmark the last 10 years.
The position is covered by
the “Memorandum on Job Structure for Academic Staff at the Universities” of
June 28, 2013.
Application
By sending an application you will
be taken in to consideration for both positions at either University of
Copenhagen or Rigshospitalet.
Your
application must be submitted electronically by clicking ‘Apply now’ below or via
BRIC’s website on http://www.bric.ku.dk/jobs/. The
application must include the following documents/attachments – all in PDF
format:
- Motivated letter of application (max. one page). Indicate preference for project 1, 2, or both.
- CV incl. education, work/research experience, language skills and other skills relevant for the position.
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
- List of publications.
- Letters of recommendation (only if shortlisted)
Application deadline: August
11, 2017.
We reserve the
right not to consider material received after the deadline, and not to consider
applications or letters of recommendation that do not live up to the
above-mentioned requirements.
The further
process
Shortlist: After expiry
of the application deadline, the superior with power to appoint selects a
number of applicants for assessment on the advice of the Appointments
Committee. All applicants are immediately notified whether their application
has been passed for assessment. Applicants who were not passed for assessment
should not expect further with regard to their application unless the shortlist
is revised.
Letters of recommendation: Furthermore,
the shortlisted applicants should each provide two letters of recommendation.
The letter must be signed by the supporting person on paper with institutional
letter head and in PDF-format. The letters should be received maximum 1 week
after shortlisting notification on jobs-vip-bric@bric.ku.dk with subject “name candidate-Sørensen-postdoc-2017”; preferably
by the supporting person. Please make sure that an easy match between the
recommendation letter and the individual applicant is possible.
Assessment: The selected
applications will be assessed according to the Ministry Order on the
Appointment of Academic Staff at Universities 2012 and the University of
Copenhagen’s guidelines 2013. The Assessment Committee makes
a non-prioritized assessment of the academic qualifications and experience with respect to the above mentioned area of research,
techniques, skills and other requirements listed in the advertisement.
University of Copenhagen and Rigshospitalet wish
to reflect the diversity of society and welcome applications from all qualified
candidates regardless of personal background.
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Jobbet er udløbet...
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Fakta
- Arbejdssted
Rigshospitalet, Blegdamsvej - Adresse
Blegdamsvej 9, 2100 København Ø -
Kontaktperson
Finn Cilius Nielsen - Stillingstype
Læge - Speciale
Klinisk biokemi & Klinisk genetik & Klinisk onkologi - Ansættelsesform
Projektansættelse - Ugentlig arbejdstid
Fuld tid - Ansættelsens start
01-10-2017 - Regionens jobnr.
206453 - Quick-nr.
320891 - Indrykningsdato
11-07-2017 -
Ansøgningsfrist
11-08-2017 (udløbet)
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