A new position as PhD-student at Functional Imaging Unit, Rigshospitalet, Glostrup, University of Copenhagen, is open for application.

Functional Imaging Unit invites applications for a fully financed 3-year PhD-student fellowship within the research project “Rehabilitation in patients with prolonged post-concussion syndrome - The REPCON project” preferably from medical doctors, or civil engineers (typically Med.Tech or similar candidates within neuroscience.

The position is open from the earliest convenience. Enrolment at the Copenhagen Graduate School of Health and Medical Sciences within 6 to 12 months from employment is a prerequisite (referring to the Ministerial Order on the PhD Program at Universities, no. 1039, 27. August 2013).

Functional Imaging Unit

Functional Imaging Unit (FIU) was established at Rigshospitalet, Glostrup in 2004 and is headed by Professor Henrik BW Larsson. FIU is part of Dept. of Clinical Physiology and Nuclear Medicine, Rigshospitalet. The general scientific aim is to bring advanced physiological or multi-modal MRI methods into clinical research based on physiological insight. Senior researchers at FIU have more than 15 years of experience in investigating neuroscience and neurological disorders using MRI and functional MRI. 

The REPCON project

The REPCON project is a large-scale collaboration project with University College Copenhagen (KP) and Norwegian University of Life Science (NMBU). The project comprises:

1. A neurobiological assessment of brain function in patients with prolonged post-concussion symptoms using functional Magnetic Resonance Imaging – the primary objective of this PhD project.
2. A specific tailored exercise interventional program for patients randomized for active treatment.
3. Qualitative assessment of patient’s perception of living with concussion symptoms
4. A 360-degree evaluation of the entire study by all participants – researchers and patients together.

The PhD project

Conventional brain imaging of patients with post-concussion symptoms, following a mild traumatic brain injury, is commonly without abnormal findings.  We hypothesize that post-concussion symptoms are related to altered subtle brain function physiology.

We will focus on the following entities:

1. Investigation of permeability of the blood-brain barrier (BBB) – we hypothesize that an abnormal leakage of the BBB will be present in the REPCON patients. During the last 20 years we have published highly novel results focusing on measuring subtle changes in permeability of the BBB by dynamic contrast-enhanced MRI (DCE-MRI), with special focus on patients with multiple sclerosis, migraine and aging.

2. Investigation of the brain’s microstructure using diffusion MRI.

3. Investigation of the brain metabolism focusing on the brains lactate production.

Supervisor: Professor Henrik BW Larsson, MD, DMSc

• Inventor of the DCE-MRI method in 1990, supervisor for 26 PhD and Master Students since 1995)

Co-supervisor: Postdoc Stig P. Cramer, MD, PhD

• Practical experience with the DCE-MRI method.

Co-supervisor:  MR-physicist Ulrich Lindberg, MSc, PhD

• MR specialist

Co-supervisor: Postdoc Mark Vestergaard,MSc, PhD

• Brain metabolism specialist

Further information: henrik.bo.wiberg.larsson@regionh.dk

PhD qualifications, conditions and procedure

The successful applicant must hold a Medical Doctors degree. Civil engineers, or candidates in neuroscience are encourage also to apply. Relevant course work, previous research and practical experience should be described. The applicant should have a high level of academic interest in the field and should possess the ability to work in multi-disciplinary teams as well as independently and collaborate with partners of the project. Interest in brain physiology, computer handling, using of advanced software for brain data processing, possible mathematic modeling, programming and statistics is an advantage.

The grant is a fully financed 3-year PhD-position. The main working place is Rigshospitalet, Glostrup.

Applications (in English or Danish) should include a short description of motivation (max. 2 pages), academic achievements, copies of degrees, and a CV.

Deadline and Submission

Deadline is 25th of March 2023.

Applications should be submitted online via the link in the job advert.

All interested parties are encouraged to apply for the position, regardless of age, sex, race, religion or ethnicity.

• Fakta

• Arbejdssted
  Rigshospitalet, Glostrup
• Kontaktperson
  Henrik Larsson
• Adresse
  Blegdamsvej 9, 2100 København Ø
• Stillingstype
  Læge
• Speciale
  klinisk fysiologi og nuklearmedicin
• Ansættelsesform
  Tidsbegrænset periode
• Ugentlig arbejdstid
  Fuld tid
• Ansættelsens start
  Snarest muligt
• Regionens jobnr.
  247924
• Quick-nr.
  445430
• Indrykningsdato
  27-02-2023
• Ansøgningsfrist
  25-03-2023 (udløbet)

Jobbet er udløbet...