Postdoc position with experience in molecular biology at Department of Clinical Microbiology, Rigshospitalet

We are looking for a postdoctoral researcher with a well-documented expertise in molecular microbiology and an interest in joining a group performing advanced research in bacterial infection mechanisms. The research area to be covered comprises genome editing of opportunistic pathogenic bacteria followed by molecular characterization of the engineered strains. The further aim of the project is to employ the constructed bacterial variants in investigations of their infection potential in a recently developed cell culture-based infection model.

The position will be placed at the main hospital in Denmark, Rigshospitalet, Copenhagen, Denmark. The proposed start date of this position is August 1, 2023, and will terminate in July 2025.

The research in the Infection Microbiology Group at RH/DTU Biosustain is part of a Novo Nordisk Foundation Challenge grant (PERFECTION) that covers bacterial phenotypes associated with one of the most urgent challenges in our society - antibiotic resistance undermining effective treatment of human bacterial infections. In the Infection Microbiology Group, headed by Professor, Consultant Helle Krogh Johansen, Rigshospitalet and Professor Søren Molin, DTU, you will be working with a common aim towards bridging the gap between academic biomedicine projects and their clinical applications. We aim at establishing and integrating a workflow, from synthetic and systems biology through genomic engineering, multi-omic data generation from bench-scale infection models, and comparisons with clinical investigations of infected patients. The Group has a total staff of approx. 15 employees, comprising a highly motivated team of engineers, scientists, clinicians, and students to tackle this challenging task. Important focus points of the project are to elucidate host/microbe interactions and responses to fluctuating environmental conditions in a newly developed miniature organ infection model (‘organoids’) and in air liquid interface cell cultures (‘ALI’) from multi-omics and bioprocess data analysis, and design of strategies for identifying and testing biomarkers for improved clinical diagnostics as well as the action of new and old types of antibiotics.

Important and required qualifications of the preferred applicants are:

• Broad experience in microbial genetics and strain constructions
• Expertise in bacterial growth and phenotypic characterization
• Experience with different -omics methods
• Excellent writing skills

Additional knowledge and experience in cell culture growth and maintenance is desirable but not required.

In addition, you must

• enjoy working with complex topics
• thrive on collaboration/teamwork with a focus on the process as well as the outcome
• believe in dialogue and feedback as the best foundation for sound decision-making

What we offer in return
We offer an interesting and challenging job in an international cross-disciplinary atmosphere with the focus on research, education, innovation, and translation of basic science results to clinical applications for the benefit of patients. We offer a great flexibility in the position, spanning several hospitals and DTU departments.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

Further information
Further information may be obtained from Professor, Consultant Helle Krogh Johansen, telephone +45 3122 8406, mail hkj@biosustain.dtu.dk

Application procedure 
Please submit your online application no later than June 1, 2023.

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English as one PDF file. The file must include:

• Application (cover letter)
• CV (including details, under appropriate headings, starting with the most recent)
• Diploma (Bachelor/Master/PhD)
• List of publications
• Letters of rekommandations 

Please note, that applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. 

• Fakta

• Arbejdssted
  Rigshospitalet, Blegdamsvej
• Kontaktperson
  Helle Krogh Johansen
• Adresse
  Blegdamsvej 9, 2100 København Ø
• Stillingstype
  Molekylærbiolog
• Ansættelsesform
  Tidsbegrænset periode
• Ugentlig arbejdstid
  Fuld tid
• Ansættelsens start
  01-08-2023
• Regionens jobnr.
  249233
• Quick-nr.
  448406
• Indrykningsdato
  01-05-2023
• Ansøgningsfrist
  01-06-2023 (udløbet)